Pharmacogenomics in Antithrombotic Therapy
Pharmacogenomics is increasingly important in personalizing antithrombotic therapy for patients at risk of thromboembolic events. By understanding how genetic variations influence drug metabolism and response, healthcare providers can optimize antiplatelet and anticoagulant treatments to maximize efficacy and minimize adverse effects. Variants in genes such as CYP2C19 and VKORC1 significantly affect patients' responses to medications like clopidogrel and warfarin. Implementing pharmacogenomic testing in clinical practice enables tailored treatment strategies, enhancing patient safety and outcomes. As pharmacogenomics continues to evolve, it will play a crucial role in personalized cardiovascular care.
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