Blood Flow in the Brain and Metabolism
Cerebral Blood Flow (CBF): CBF is defined as the amount of blood that flows through brain tissue per unit mass per unit of time and is often measured in milliliter’s (ml) of blood. Single-photon outflow registered tomography (SPECT), positron discharge tomography (PET), X-ray with contrast agents, and blood vessel turn marking (ASL) X-ray are direct methods for determining CBF in human individuals.
Four main mechanisms regulate CBF:
- Metabolic regulation, sometimes known as "metabolic auto regulation "
- automatic pressure regulation
- Chemical regulation (by arterial pCO2 and pO2)
- Neural command
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